Abstract A mixed design was created using text and game-like multimedia to instruct in the content of physics.The study assessed which variables predicted learning gains after a 1-h lesson on the electric field.The three manipulated variables were: (1) level of embodiment; (2) level of active generativity; and (3) presence of story narrative.Two ty
The roles of epigallocatechin gallate in the tumor microenvironment, metabolic reprogramming, and immunotherapy
Cancer, a disease that modern medicine has not fully understood and conquered, with its high incidence and mortality, deprives countless patients of health and even life.According to global cancer statistics, there were an estimated 19.3 million new cancer cases and nearly 10 million cancer deaths in 2020, with the age-standardized incidence and mo
Colonocyte-derived lactate promotes E. coli fitness in the context of inflammation-associated gut microbiota dysbiosis
Abstract Background Intestinal inflammation disrupts the microbiota composition leading to an expansion of Enterobacteriaceae family members (dysbiosis).Associated with this shift in microbiota composition is a profound change in the metabolic landscape of the intestine.It is unclear how changes in metabolite availability during gut inflammation im
Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments
The ferret transmission model is extensively used to assess the pandemic potential of emerging influenza viruses, yet experimental conditions and reported results vary among laboratories.Such variation can be a critical consideration when contextualizing results from independent risk-assessment studies of novel and emerging influenza viruses.To str
Preoperative portal vein embolization followed by right hepatectomy to treat a complex common bile duct injury in a 5-year-old child
Background Common bile duct injuries (CBDIs) remains a rare but serious complication in children undergoing MCT laparoscopic cholecystectomy (LC), with an incidence of 0.44%.In severe lesions, a major liver resection may be necessary as a definitive treatment.The current principles for safe hepatectomy are mainly focused on the liver parenchyma tha